{"id":4077,"date":"2015-12-15T19:04:27","date_gmt":"2015-12-15T17:04:27","guid":{"rendered":"http:\/\/www.vandaomeopatici.it\/it\/?p=4077"},"modified":"2023-06-15T14:27:52","modified_gmt":"2023-06-15T12:27:52","slug":"scienza-omeopatia-2","status":"publish","type":"post","link":"https:\/\/www.vandaomeopatici.it\/it\/scienza-omeopatia-2\/","title":{"rendered":"Cell sensitivity, non-linearity and inverse effects"},"content":{"rendered":"

Segnaliamo la pubblicazione di questo articolo. Tratto da “Homeopathy”,\u00a0April 2015<\/a>\u00a0Volume 104, Issue 2, Pages\u00a0139\u2013160. Redazione.<\/em><\/strong><\/p>\n

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Introduction:\u00a0cell-sensitivity, effetto non lineare e effetto inverso. Scienza omeopatia.<\/h1>\n

Paolo Bellavite<\/a>\u00a0(Department of Pathology and Diagnostics, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy), \u00a0Andrea Signorini<\/a>, Marta Marzotto <\/a>(Department of Pathology and Diagnostics, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy), Elisabetta Moratti <\/a>(Department of Pathology and Diagnostics, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy), Clara Bonafini<\/a> (Department of Pathology and Diagnostics, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy), Debora Olioso<\/a> (Department of Pathology and Diagnostics, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy)<\/p>\n

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According to the \u2018similarity\u2019 (or \u2018similia\u2019) principle, patients can be cured using low doses or high dilutions\/dynamizations of a drug that in healthy people produces similar symptoms to the disease. However, this approach is regarded as unscientific by some circles.\u00a0One current opinion about homeopathic treatment associates this medical approach with the placebo effect, either because of some highly publicized meta-analysis\u00a0or because of the alleged implausibility of its theories.\u00a0<\/span>While controversies concerning the clinical efficacy have been recently discussed by others,\u00a0here we survey the homeopathic basic principles with the aim of examining their consistency with modern scientific knowledge of biological communication at cellular and molecular levels. The low dose effects and the healing power of pathogenic substances observed in homeopathy, are linked to the high sensitivity of biological systems at various levels of organization and to the multiform ways through which the complex of mind-body homeodynamic regulations (\u2018vital force\u2019) reacts to external stimuli. Growing evidence from several science fields suggests that hormesis and paradoxical pharmacology are included in the \u2018adaptation\u2019 capacity of immune, neuroendocrine and cardiovascular systems, but also in cellular defence\/repair mechanisms and even in molecular dynamics and conformational changes.\u00a0<\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n

Our working hypothesis is that recognition of the function of enzymes, receptors and signal transduction and their dynamic interaction with drugs, makes it possible to look at homeopathy in a new and fully rational light. The cornerstone of homeopathy \u2013 that the whole clinical picture of the individual patient to be taken into consideration \u2013 is not in dispute, but laboratory models also allow the mechanism(s) of action of drugs to be investigated in animals, cells, tissues, and even at the molecular level. This \u2018reductionistic\u2019 perspective is not in contrast with the \u2018holistic\u2019 approach of homeopathy as a healing system, but rather represents the fundamental basis of a developing theory which would include recent advancements in complexity science and systems biology.\u00a0<\/span>Given the holographic and fractal nature of all complex systems, the fundamental characteristics and rules of biological responses and related pathologies can be unravelled at any level of nature.<\/p>\n

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